TOLSURA SUBA™ Technology
![](https://newtstudios.com/wp-content/uploads/2021/02/Capsul.png)
We created this MOA animation to demonstrate Mayne Pharma’s innovative SUBA™ technology in TOLSURA‘s formulation.
SUBA™ technology enhances the solubility and absorption of poorly soluble drugs like conventional itraconazole.
The Newt Studios team animated the novel SUBA™ process that produces nano-size, amorphous drug particles dispersed in a polymer matrix, instead of the conventional crystalline form.
TOLSURA is an orally administered broad-spectrum anti-fungal agent that contains the active ingredient itraconazole and has proven efficacy in the treatment of endemic and systemic mycoses.
3D Production: Newt Studios
Agency: Dagr Nott & Associates
Client: Mayne Pharma
TOLSURA 3D Bottle, Capsule and Figure with Gastrointestinal Tract
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_17.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_16.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_15.jpg)
3D Figure and Gastrointestinal Tract
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_05.jpg)
Absorption in the Small Intestine
The large surface area of the small intestine’s villi and nano-size particles of the SUBA-itraconazole formulation improve bioavailability and reduce variability in plasma levels within a patient.
![](https://newtstudios.com/wp-content/uploads/2021/02/Inner_Body_v01_OUT_ak.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_08-1.jpg)
Conventional Itraconazole Crystals and Microscopic SUBA Particles
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_11.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_12.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_13.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_06.jpg)
SUBA Spray-drying Technology – 2D Animated Elements
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_02-2.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_03-2.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/02/Tolsura_09.jpg)
Please visit tolsura.com for more information.
More work
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