Pathophysiology of Molluscum Contagiosum
![](https://newtstudios.com/wp-content/uploads/2021/06/molluscum.png)
Mechanism of disease (MOD) animation produced to describe molluscum contagiosum – an infection caused by a poxvirus resulting in umbilicated papules on the surface of the skin. Scratching or touching the lesions can spread the viral infection to the surrounding skin.
Molluscum is a common, benign, yet highly contagious skin disease that affects an estimated six million people in the United States, primarily children.
The Newt Studios team animated the poxvirus invading their target – basal epithelial cells, which then proliferate rapidly in the process of hyperplasia. Viral-inclusion bodies assemble and grow inside the basal cells as the virus replicates over time.
Many thank yous to the incredible One World team for their partnership in script-writing, storyboarding, and medical direction. Our collaboration elevated the science story for the client’s healthcare professional audience.
3D Production: Newt Studios
Medical and Creative Collaboration: One World Design and Manufacturing Group
Client: Verrica Pharmaceuticals
Scroll down to view our 3D process and animation development.
3D Modeling the Epidermis in ZBrush
![](https://newtstudios.com/wp-content/uploads/2021/06/008.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/06/039.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/06/037.jpg)
Texturing the Skin and Lesions
![](https://newtstudios.com/wp-content/uploads/2021/06/029.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/06/034.jpg)
Storyboard Animatic depicting the Histopathology
As the molluscum bodies enlarge and keratinize, the cells organize into follicles and lobes, develop a central indentation, and ultimately form into distinctive raised lesions.
Virus Morphology and Basal Cell Hyperplasia – 3D Development
Molluscum Contagiousum Poxvirus
![](https://newtstudios.com/wp-content/uploads/2021/06/Newt-Studios_MCV_virus_01.jpg)
Skin Lesions and Inflammation
![](https://newtstudios.com/wp-content/uploads/2021/06/Newt-Studios_MCV_lesion_03.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/06/Newt-Studios_MCV_lesion_02.jpg)
![](https://newtstudios.com/wp-content/uploads/2021/06/Newt-Studios_MCV_lesion_01.jpg)
Healthy Epidermis
![](https://newtstudios.com/wp-content/uploads/2021/06/Newt-Studios_MCV_epithelium_01.jpg)
2D Graphics Development
![](https://newtstudios.com/wp-content/uploads/2021/06/Animatic_OUT_2.gif)
![](https://newtstudios.com/wp-content/uploads/2021/06/Animatic_OUT_4.gif)
For more project information and visuals please visit our Behance.net page.
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